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Zhong Q
,
Rüschoff JH
,
Guo T
,
Gabrani M
,
Schüffler PJ
,
Rechsteiner M
,
Liu Y
,
Fuchs TJ
,
Rupp NJ
,
Fankhauser C
et al.
. 2016.
Image-based computational quantification and visualization of genetic alterations and tumour heterogeneity.
.
Sci Rep. 6:24146.
Zhao X
,
Weir BA
,
LaFramboise T
,
Lin M
,
Beroukhim R
,
Garraway L
,
Beheshti J
,
Lee JC
,
Naoki K
,
Richards WG
et al.
. 2005.
Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis.
.
Cancer Res. 65(13):5561-70.
V
Varambally S
,
Yu J
,
Laxman B
,
Rhodes DR
,
Mehra R
,
Tomlins SA
,
Shah RB
,
Chandran U
,
Monzon FA
,
Becich MJ
et al.
. 2005.
Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression.
.
Cancer Cell. 8(5):393-406.
T
Tomlins SA
,
Bjartell A
,
Chinnaiyan AM
,
Jenster G
,
Nam RK
,
Rubin MA
,
Schalken JA
. 2009.
ETS gene fusions in prostate cancer: from discovery to daily clinical practice.
.
Eur Urol. 56(2):275-86.
Tomlins SA
,
Rhodes DR
,
Perner S
,
Dhanasekaran SM
,
Mehra R
,
Sun X-W
,
Varambally S
,
Cao X
,
Tchinda J
,
Kuefer R
et al.
. 2005.
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.
.
Science. 310(5748):644-8.
S
Svensson MA
,
Lafargue CJ
,
MacDonald TY
,
Pflueger D
,
Kitabayashi N
,
Santa-Cruz AM
,
Garsha KE
,
Sathyanarayana UG
,
Riley JP
,
Yun CS
et al.
. 2011.
Testing mutual exclusivity of ETS rearranged prostate cancer.
.
Lab Invest. 91(3):404-12.
Stark JR
,
Perner S
,
Stampfer MJ
,
Sinnott JA
,
Finn S
,
Eisenstein AS
,
Ma J
,
Fiorentino M
,
Kurth T
,
Loda M
et al.
. 2009.
Gleason score and lethal prostate cancer: does 3 + 4 = 4 + 3?
J Clin Oncol. 27(21):3459-64.
Sreekumar A
,
Laxman B
,
Rhodes DR
,
Bhagavathula S
,
Harwood J
,
Giacherio D
,
Ghosh D
,
Sanda MG
,
Rubin MA
,
Chinnaiyan AM
. 2004.
Humoral immune response to alpha-methylacyl-CoA racemase and prostate cancer.
.
J Natl Cancer Inst. 96(11):834-43.
Shah RB
,
Mehra R
,
Chinnaiyan AM
,
Shen R
,
Ghosh D
,
Zhou M
,
Macvicar GR
,
Varambally S
,
Harwood J
,
Bismar TA
et al.
. 2004.
Androgen-independent prostate cancer is a heterogeneous group of diseases: lessons from a rapid autopsy program.
.
Cancer Res. 64(24):9209-16.
Setlur SR
,
Mertz KD
,
Hoshida Y
,
Demichelis F
,
Lupien M
,
Perner S
,
Sboner A
,
Pawitan Y
,
Andrén O
,
Johnson LA
et al.
. 2008.
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer.
.
J Natl Cancer Inst. 100(11):815-25.
Setlur SR
,
Royce TE
,
Sboner A
,
Mosquera J-M
,
Demichelis F
,
Hofer MD
,
Mertz KD
,
Gerstein M
,
Rubin MA
. 2007.
Integrative microarray analysis of pathways dysregulated in metastatic prostate cancer.
.
Cancer Res. 67(21):10296-303.
Setlur SR
,
Rubin MA
. 2005.
Current thoughts on the role of the androgen receptor and prostate cancer progression.
.
Adv Anat Pathol. 12(5):265-70.
Schlick B
,
Massoner P
,
Lueking A
,
Charoentong P
,
Blattner M
,
Schaefer G
,
Marquart K
,
Theek C
,
Amersdorfer P
,
Zielinski D
et al.
. 2016.
Serum Autoantibodies in Chronic Prostate Inflammation in Prostate Cancer Patients.
.
PLoS One. 11(2):e0147739.
Sboner A
,
Habegger L
,
Pflueger D
,
Terry S
,
Chen DZ
,
Rozowsky JS
,
Tewari AK
,
Kitabayashi N
,
Moss BJ
,
Chee MS
et al.
. 2010.
FusionSeq: a modular framework for finding gene fusions by analyzing paired-end RNA-sequencing data.
.
Genome Biol. 11(10):R104.
Sboner A
,
Demichelis F
,
Calza S
,
Pawitan Y
,
Setlur SR
,
Hoshida Y
,
Perner S
,
Adami H-O
,
Fall K
,
Mucci LA
et al.
. 2010.
Molecular sampling of prostate cancer: a dilemma for predicting disease progression.
.
BMC Med Genomics. 3:8.
Santagata S
,
Demichelis F
,
Riva A
,
Varambally S
,
Hofer MD
,
Kutok JL
,
Kim R
,
Tang J
,
Montie JE
,
Chinnaiyan AM
et al.
. 2004.
JAGGED1 expression is associated with prostate cancer metastasis and recurrence.
.
Cancer Res. 64(19):6854-7.
Sailer V
,
Pauli C
,
Merzier EC
,
Mosquera JMiguel
,
Beltran H
,
Rubin MA
,
Rao RA
. 2017.
On-site Cytology for Development of Patient-Derived Three-dimensional Organoid Cultures - A Pilot Study.
.
Anticancer Res. 37(4):1569-1573.
R
Rubin MA
,
Allory Y
,
Molinié V
,
Leroy X
,
Faucon H
,
Vacherot F
,
Huang W
,
Kuten A
,
Salomon L
,
Rebillard X
et al.
. 2005.
Effects of long-term finasteride treatment on prostate cancer morphology and clinical outcome.
.
Urology. 66(5):930-4.
Rubin MA
,
Elemento O
,
Sboner A
,
Imielinski M
,
Pisapia D
,
Fernandes H
,
Zia H
,
Huang L
,
Tavassoli P
,
Kluk M
. 2016.
The cancer precision medicine knowledge base for structured clinical-grade mutations and interpretation
.
JAMIA.
Rubin MA
. 2015.
Toward a prostate cancer precision medicine.
.
Urol Oncol. 33(2):73-4.
Rubin MA
,
Maher CA
,
Chinnaiyan AM
. 2011.
Common gene rearrangements in prostate cancer.
.
J Clin Oncol. 29(27):3659-68.
Rubin MA
,
Bismar TA
,
Andrén O
,
Mucci L
,
Kim R
,
Shen R
,
Ghosh D
,
Wei JT
,
Chinnaiyan AM
,
Adami H-O
et al.
. 2005.
Decreased alpha-methylacyl CoA racemase expression in localized prostate cancer is associated with an increased rate of biochemical recurrence and cancer-specific death.
.
Cancer Epidemiol Biomarkers Prev. 14(6):1424-32.
Rubin MA
,
Zerkowski MP
,
Camp RL
,
Kuefer R
,
Hofer MD
,
Chinnaiyan AM
,
Rimm DL
. 2004.
Quantitative determination of expression of the prostate cancer protein alpha-methylacyl-CoA racemase using automated quantitative analysis (AQUA): a novel paradigm for automated and continuous biomarker measurements.
.
Am J Pathol. 164(3):831-40.
Rubin MA
,
Chinnaiyan AM
. 2006.
Bioinformatics approach leads to the discovery of the TMPRSS2:ETS gene fusion in prostate cancer.
.
Lab Invest. 86(11):1099-102.
Rubin MA
,
Girelli G
,
Demichelis F
. 2016.
Genomic Correlates to the Newly Proposed Grading Prognostic Groups for Prostate Cancer.
.
Eur Urol. 69(4):557-60.
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