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I
Imielinski M
,
Rubin MA
. 2017.
Prostate cancer: Clinical hallmarks in whole cancer genomes.
.
Nat Rev Clin Oncol.
K
Kelly KA
,
Setlur SR
,
Ross R
,
Anbazhagan R
,
Waterman P
,
Rubin MA
,
Weissleder R
. 2008.
Detection of early prostate cancer using a hepsin-targeted imaging agent.
.
Cancer Res. 68(7):2286-91.
Khurana E
,
Fu Y
,
Chakravarty D
,
Demichelis F
,
Rubin MA
,
Gerstein M
. 2016.
Role of non-coding sequence variants in cancer.
.
Nat Rev Genet. 17(2):93-108.
Kim R
,
Demichelis F
,
Tang J
,
Riva A
,
Shen R
,
Gibbs DF
,
Mahavishno V
,
Chinnaiyan AM
,
Rubin MA
. 2005.
Internet-based Profiler system as integrative framework to support translational research.
.
BMC Bioinformatics. 6:304.
Kumar-Sinha C
,
Shah RB
,
Laxman B
,
Tomlins SA
,
Harwood J
,
Schmitz W
,
Conzelmann E
,
Sanda MG
,
Wei JT
,
Rubin MA
et al.
. 2004.
Elevated alpha-methylacyl-CoA racemase enzymatic activity in prostate cancer.
.
Am J Pathol. 164(3):787-93.
L
Lin P-C
,
Chiu Y-L
,
Banerjee S
,
Park K
,
Mosquera JMiguel
,
Giannopoulou E
,
Alves P
,
Tewari AK
,
Gerstein MB
,
Beltran H
et al.
. 2013.
Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression.
.
Cancer Res. 73(3):1232-44.
M
Mateo J
,
Carreira S
,
Sandhu S
,
Miranda S
,
Mossop H
,
Perez-Lopez R
,
Rodrigues DNava
,
Robinson D
,
Omlin A
,
Tunariu N
et al.
. 2015.
DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer.
.
N Engl J Med. 373(18):1697-708.
Mateo J
,
Boysen G
,
Barbieri CE
,
Bryant HE
,
Castro E
,
Nelson PS
,
Olmos D
,
Pritchard CC
,
Rubin MA
,
de Bono JS
. 2016.
DNA Repair in Prostate Cancer: Biology and Clinical Implications.
.
Eur Urol.
Mertz KD
,
Demichelis F
,
Kim R
,
Schraml P
,
Storz M
,
Diener P-A
,
Moch H
,
Rubin MA
. 2007.
Automated immunofluorescence analysis defines microvessel area as a prognostic parameter in clear cell renal cell cancer.
.
Hum Pathol. 38(10):1454-62.
Mertz KD
,
Setlur SR
,
Dhanasekaran SM
,
Demichelis F
,
Perner S
,
Tomlins S
,
Tchinda J
,
Laxman B
,
Vessella RL
,
Beroukhim R
et al.
. 2007.
Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model.
.
Neoplasia. 9(3):200-6.
Mertz KD
,
Demichelis F
,
Sboner A
,
Hirsch MS
,
Dal Cin P
,
Struckmann K
,
Storz M
,
Scherrer S
,
Schmid DM
,
Strebel RT
et al.
. 2008.
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer.
.
Int J Cancer. 123(3):569-76.
Mosquera J-M
,
Perner S
,
Demichelis F
,
Kim R
,
Hofer MD
,
Mertz KD
,
Paris PL
,
Simko J
,
Collins C
,
Bismar TA
et al.
. 2007.
Morphological features of TMPRSS2-ERG gene fusion prostate cancer.
.
J Pathol. 212(1):91-101.
Mosquera J-M
,
Perner S
,
Genega EM
,
Sanda M
,
Hofer MD
,
Mertz KD
,
Paris PL
,
Simko J
,
Bismar TA
,
Ayala G
et al.
. 2008.
Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications.
.
Clin Cancer Res. 14(11):3380-5.
Mosquera JMiguel
,
Beltran H
,
Park K
,
MacDonald TY
,
Robinson BD
,
Tagawa ST
,
Perner S
,
Bismar TA
,
Erbersdobler A
,
Dhir, iv R
et al.
. 2013.
Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer.
.
Neoplasia. 15(1):1-10.
Mosquera J-M
,
Varma S
,
Pauli C
,
MacDonald TY
,
Yashinskie JJ
,
Varga Z
,
Sboner A
,
Moch H
,
Rubin MA
,
Shin SJ
. 2015.
MAGI3-AKT3 fusion in breast cancer amended.
.
Nature. 520(7547):E11-2.
Mosquera J-M
,
Mehra R
,
Regan MM
,
Perner S
,
Genega EM
,
Bueti G
,
Shah RB
,
Gaston S
,
Tomlins SA
,
Wei JT
et al.
. 2009.
Prevalence of TMPRSS2-ERG fusion prostate cancer among men undergoing prostate biopsy in the United States.
.
Clin Cancer Res. 15(14):4706-11.
Mu P
,
Zhang Z
,
Benelli M
,
Karthaus WR
,
Hoover E
,
Chen C-C
,
Wongvipat J
,
Ku S-Y
,
Gao D
,
Cao Z
et al.
. 2017.
SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer.
.
Science. 355(6320):84-88.
P
Park K
,
Dalton JT
,
Narayanan R
,
Barbieri CE
,
Hancock ML
,
Bostwick DG
,
Steiner MS
,
Rubin MA
. 2014.
TMPRSS2:ERG gene fusion predicts subsequent detection of prostate cancer in patients with high-grade prostatic intraepithelial neoplasia.
.
J Clin Oncol. 32(3):206-11.
Park K
,
Tomlins SA
,
Mudaliar KM
,
Chiu Y-L
,
Esgueva R
,
Mehra R
,
Suleman K
,
Varambally S
,
Brenner JC
,
MacDonald T
et al.
. 2010.
Antibody-based detection of ERG rearrangement-positive prostate cancer.
.
Neoplasia. 12(7):590-8.
Pauli C
,
Hopkins BD
,
Prandi D
,
Shaw R
,
Fedrizzi T
,
Sboner A
,
Sailer V
,
Augello M
,
Puca L
,
Rosati R
et al.
. 2017.
Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine.
.
Cancer Discov.
Pauli C
,
Puca L
,
Mosquera JMiguel
,
Robinson BD
,
Beltran H
,
Rubin MA
,
Rao RA
. 2016.
An emerging role for cytopathology in precision oncology.
.
Cancer Cytopathol. 124(3):167-73.
Perner S
,
Demichelis F
,
Beroukhim R
,
Schmidt FH
,
Mosquera J-M
,
Setlur S
,
Tchinda J
,
Tomlins SA
,
Hofer MD
,
Pienta KG
et al.
. 2006.
TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer.
.
Cancer Res. 66(17):8337-41.
Perner S
,
Hofer MD
,
Kim R
,
Shah RB
,
Li H
,
Möller P
,
Hautmann RE
,
Gschwend JE
,
Kuefer R
,
Rubin MA
. 2007.
Prostate-specific membrane antigen expression as a predictor of prostate cancer progression.
.
Hum Pathol. 38(5):696-701.
Perner S
,
Svensson MA
,
Hossain RR
,
Day JR
,
Groskopf J
,
Slaughter RC
,
Jarleborn AR
,
Hofer MD
,
Kuefer R
,
Demichelis F
et al.
. 2010.
ERG rearrangement metastasis patterns in locally advanced prostate cancer.
.
Urology. 75(4):762-7.
Perner S
,
Wagner PL
,
Soltermann A
,
LaFargue C
,
Tischler V
,
Weir BA
,
Weder W
,
Meyerson M
,
Giordano TJ
,
Moch H
et al.
. 2009.
TTF1 expression in non-small cell lung carcinoma: association with TTF1 gene amplification and improved survival.
.
J Pathol. 217(1):65-72.
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