Genomics Laboratory Technical Specialist (Date Posted: 12/28/2015)

Position Summary

This Genomics Laboratory Technical Specialist, for the Precision Medicine Genomics CLIA-certified lab, will utilize advanced laboratory techniques, computer and bioinformatics skills to develop, validate, perform and troubleshoot complex genomic testing using next generation sequencing technologies.  This role requires following regulatory requirements, quality assurance and quality control principles. This person will work closely with laboratory manager, laboratory directors and medical director to plan and implement NGS assays for clinical testing.  

Position Activities

• Develops and validates Next Generation Sequencing (NGS) assays for clinical testing. This includes planing, implementing and documenting clinical validation studies for NGS assays. Works closely with manufacturers to implement necessary assays. Defines and documents clinical validation plans. Performs development and validation studies to ensure timely completion, per project deadlines. Documents and prepares development validation studies for review by the Laboratory/Medical Directors.
• Performs the technical duties using a variety of techniques including: DNA extraction, NGS, Sanger sequencing, capillary electrophoresis, and other DNA and RNA-based assays, as necessary. Coordinates with laboratory staff to obtain and finalize SOPs, assay controls, quality controls and reagents.
• Maintains required assay documentation including proper specimen handling, labeling and preparation of worksheets. Updates protocols and databases associated with clinical testing.
• Work with internal and external (vendor) bioinformatics colleagues in order to facilitate data analysis, and data maintenance/data storage.
• Assists with instruction and supervision of students, residents and fellows during their rotations in the molecular genomic clinical laboratory. 

Performs other related duties as assigned.